Korean J Dermatol.  2006 Oct;44(10):1231-1234.

Pulsed Intravenous Immunoglobulin Therapy in Livedo Vasculitis: Report of Two Cases

• Byun HJ
• Park HS
• Min SU
• Shin HS
• Li K
• Won CH
• Cho S

Abstract

Livedo vasculitis is a chronic dermatosis characterized by recurrent painful ulceration of the lower limbs, which heals to leave atrophie blanche. The precise pathophysiology is not known. Antiplatelet, anticoagulant, fibrinolytic therapies and anabolic steroids have been reported to be helpful in this syndrome. However, no consistent benefit has been demonstrated with any treatment modality. Recently, pulsed intravenous immunoglobulin therapy has been reported to be effective in some refractory cases. We herein report two cases of recalcitrant livedo vasculitis which were effectively treated with pulsed intravenous immunoglobulin therapy. These were the first trials carried out in Korea.

Keyword

Intravenous immunoglobulin; Livedo vasculitis

MeSH Terms

Immunization, Passive*
Immunoglobulins*
Korea
Lower Extremity
Skin Diseases
Steroids
Thrombolytic Therapy
Ulcer
Vasculitis*
Immunoglobulins
Steroids