Korean J Dermatol.  1996 Oct;34(5):842-846.

A Case of Cutaneous Ossification in Pseudohypoparathyroidism

Affiliations
  • 1Department of Dermatology, Fatima Hospital, Korea.
  • 2Department of Dermatology Kyungpook National University, School of Medicine Taequ, Korea.

Abstract

A 6-month-old female infant pre~sented with multiple, slightly depressed pea-sized erythematous macules on. the abdomen and the chest since birth, which together with obese, short stature, short neck, and round face suggested Albrights hereditary osteodystrophy(AHO). Some of the lesions were palpable as hard nodules or plaques in deep dermis. After 3 months follow up, the erythem- atous hue faded out, subcutaneous nodules and plaques enlarged. Skin biopsy specirnen demonstrated a bone formation in deep dermis. Serum calcium and phosphorus levels were lower and upper normal ranges, respectively and serum parathyroid hormone was increased in 69.1 pg/ml (normal, 9-55pg/ml). As pseudohypoparathyroidism including this case mostly exhibit characteristic morphologic features of AHO, the subcutaneous ossification may be a presenting feature.

Keyword

Ossification; seudohypoparathyroidism

MeSH Terms

Abdomen
Biopsy
Calcium
Dermis
Female
Follow-Up Studies
Humans
Infant
Neck
Osteogenesis
Parathyroid Hormone
Parturition
Phosphorus
Pseudohypoparathyroidism*
Reference Values
Skin
Thorax
Calcium
Parathyroid Hormone
Phosphorus
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