Korean J Thorac Cardiovasc Surg.
2005 Mar;38(3):245-248.
Ergotamine-induced Vasospasm
- Affiliations
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- 1Department of Thoracic and Cardiovascular Surgery, Bundang CHA General Hospital, Pochon CHA University, Korea. gunlee@cvnet.co.kr
Abstract
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Drugs containing ergotamine are widely used in the treatment of migraine. Spastic vasoconstriction is one of the most serious side effects even with recommended dosage. We report a case of 63-year-old male with severe arterial occlusion of the upper limbs which might be related with vasospasm caused by ergotamine-containing medication because of migraine for 15 years. He was treated with bypass graft, sympathicotomy and heparin and prostaglandin E1 infusion. But dramatic clinical reversal of the vasospasm was obtained after withdrawal of ergotamine.