Korean J Urol.  2014 Apr;55(4):245-248. 10.4111/kju.2014.55.4.245.

Detection Rate of Prostate Cancer on the Basis of the Vienna Nomogram: A Singapore Study

Affiliations
  • 1Department of Urology, Changi General Hospital, Singapore. jin_kiat_teo@cgh.com.sg
  • 2Department of Urology, Raffles Hospital, Singapore.

Abstract

PURPOSE
The purpose of this study was to determine the efficacy of the Vienna nomogram prostate biopsy model in the detection of prostate cancer in our local population. We also assessed the incidence of complications from using such a template.
MATERIALS AND METHODS
From January 2006 to June 2007, 120 men with either elevated prostate-specific antigen (PSA) scores (>4 ng/mL) and/or abnormal digital rectal examination were enrolled prospectively to undergo extraction of 6 to 18 cores for transrectal ultrasound-guided prostate biopsy, as indicated by the Vienna nomogram.
RESULTS
The mean age was 62.6+/-8.3 years (range, 40-86 years). The mean PSA score was 13.42 ng/mL. The mean number of cores obtained was 9.68+/-3.1. According to the Vienna nomogram, 27 out of a total of 120 patients had prostate cancer, for a detection rate of 22.5%. In the group of patients with PSA scores <10 ng/mL, the detection rate was 14.9% (14 of 94 patients). The group of patients with PSA scores >10 ng/mL had a detection rate of 50% (13 of 26). The complication rate in our study was 7.5%.
CONCLUSIONS
With the use of the Vienna nomogram, our prostate cancer detection rate is comparable to previously published data for Asian patients. This nomogram offers an easy tool with which to select the optimal number of prostate biopsy cores to be taken on the basis of patient age and total prostate volume. With this biopsy strategy, we also have found that the complication rate from prostate biopsy is low.

Keyword

Biopsy; Nomogram; Prostate neoplasms

MeSH Terms

Asian Continental Ancestry Group
Biopsy
Digital Rectal Examination
Humans
Incidence
Male
Nomograms*
Prospective Studies
Prostate*
Prostate-Specific Antigen
Prostatic Neoplasms*
Singapore*
Prostate-Specific Antigen

Figure

  • FIG. 1 Histopathological breakdown of the prostate cancer patients.


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