Chonnam Med J.  2000 Sep;36(3):311-316.

Seven Cases of Hemolytic Uremic Syndrome Presenting with Bloody Diarrhea in Children

• Rha JY
• Kim BJ
• Ma JS

Abstract

We reviewed the medical records of 7 children (4 girls, 3 boys), diagnosed as hemolytic uremic syndrome (HUS) at Chonnam National University Hospital over a 10 year period (from Jan. 1990 to Dec. 1999). The age of presentation was below 5 years in 5 cases and above 12 years in 2 cases, with a mean age of 5.8 years (range 26 months-14 years). All the cases occurred between spring and summer seasons and bloody diarrhea as prodromal symptom was observed in all of them. The acute stage of the disease occurred with presentation of anuria (28.6%), oliguria (100%), hypertension (100%), seizure attacks (42.9%) and alteration of consciousness (71.4%). Six of the patients presented the full clinical syndrome; acute renal failure in 7, hemolytic anemia in 6, and thrombocytopenia in 7. Three patients with acute renal failure (42.9%) required hemodialysis. All of the patients recovered renal function, but abnormal findings of urinalysis including variable degree of proteinuria and microscopic hematuria were seen at discharge. In conclusion, all of the children with typical HUS in this study recovered from acute renal failure. Studies to further characterize the epidermiologic features and long-term outcome in HUS are needed.

Keyword

Hemolytic uremic syndrome; Child

MeSH Terms

Acute Kidney Injury
Anemia, Hemolytic
Anuria
Child*
Consciousness
Diarrhea*
Female
Hematuria
Hemolytic-Uremic Syndrome*
Humans
Hypertension
Jeollanam-do
Medical Records
Oliguria
Prodromal Symptoms
Proteinuria
Renal Dialysis
Seasons
Seizures
Thrombocytopenia
Urinalysis