Brain Tumor Res Treat.  2015 Apr;3(1):56-59. 10.14791/btrt.2015.3.1.56.

The Olfactory Groove Schwannoma Attached to the Cribriform Plate: A Case Report

• Kim DY
• Yoon PH
• Kie JH
• Yang KH

• KMID: 1882013
• DOI: http://doi.org/10.14791/btrt.2015.3.1.56

Abstract

The olfactory groove schwannoma is a quite rare tumor. We report a case of a 49-year-old woman with an olfactory groove schwannoma attached to the cribriform plate without olfactory dysfunction. She had no specific neurological symptoms other than a headache, and resection of the tumor showed it to be a schwannoma. About 19 months after the operation, a follow-up MRI showed no evidence of tumor recurrence. Surgical resection through subfrontal approach could be one of the curative modality in managing an olfactory groove schwannoma. An olfactory groove schwannoma should be considered in the differential diagnosis of anterior skull base tumors.

Keyword

Neurilemmoma; Prefrontal cortex; Ethmoid bone

MeSH Terms

Diagnosis, Differential
Ethmoid Bone*
Female
Follow-Up Studies
Headache
Humans
Magnetic Resonance Imaging
Middle Aged
Neurilemmoma*
Prefrontal Cortex
Recurrence
Skull Base

Figure

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  Fig. 1 Computed tomography scans showing a low density lesion in the left frontal lobe.

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  Fig. 2 T1-weighted coronal (A) and sagittal image (B) with gadolinium, showing a solid enhancement of the tumor in the left frontal base. T2-weighted axial MRI revealing an interspersed high signal intensity in the mass, implying cystic component (C). T1-weighted MRI with gadolinium showing a 3 cm sized variegating enhanced mass attached to the cribriform plate (D).

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  Fig. 3 Pathologic findings. A: On histological examination, the tumor is composed of spindle-shaped cells (arrows) with elongated nuclei and fibrillary cytoplasm (Antoni A pattern), and less cellular areas (Antoni B). B: On high power, Verocay bodies (thick arrows), which are acellular areas surrounded by nuclear palisades composed of spindle cells (thin arrows), the characteristics of schwannoma are well observed (H&E, ×200). C: These spindle cells (arrows) show diffuse and strong immunoreactivity for S-100 protein (×200).

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  Fig. 4 Post op MRI with gadolinium enhancement. No evidence of local tumor recurrence. An axial view of the T1-weighted gadolinium enhancement (A), a coronal view of T1-weighted gadolinium enhancement (B).

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  Fig. 5 Follow-up MRI 19 months after operation. No evidence of local tumor recurrence. An axial view of T1-weighted gadolinium enhancement (A), a coronal view of T1-weighted gadolinium enhancement (B).

Reference

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