Experiences of the Treatment of Laryngeal Cancer in Yongdong Severance Hospital

Kim, Kwang Moon; Kim, Hong Yoon; Choi, Hong Shik; Kim, Young Ho; Cho, Jung Il; Kim, Se Heon; Han, Jae Wook

Abstract

BACKGROUND AND OBJECTS: Laryngeal cancer is a significant disease in the head and neck malignancy in the aspect of incidence. But, an accurate statistical analysis of long term results is insufficient in Korea. To improve the results of treatment in laryngeal cancer, we evaluate the survival rates according to the primary site, stage and investigating factors.
MATERIALS AND METHODS
The study group was made up of 132 patients with squamous cell cancer. They had been treated for laryngeal cancer in our hospital for 11 years from 1985 to 1995. The distribution rates of patients were obtained by the discriptive statistical method according to the sex, age, pathology, primary site and stage. Survival rates were obtained by the Kaplan-Meier method according to the primary site and stage. The AJCC (1992) staging system was used.
RESULTS
With respect to the primary site, the survival rate for 5 years was 52.8% in supraglottis and 71.6% in glottis. With respect to the stage, the survival rate was 82.4% in the stage I, 60.3% in the stage II, 53.8% in the stage III and 28.6% in the stage IV. The 5-year survival rate for patients who had taken radiotherapy in T1 glottic cancer was 73.5% for the group involved with anterior commissure and 96.2% for the group not involved. In the advanced laryngeal cancer, treatment failure was influenced by nodal and stomal recurrence.
CONCLUSION
For those patients with T 1 laryngeal cancer and who recieved radiotherapy, a significant prognostic factor was whether or not the patients were involved with anterior commissure. Another important prognostic factor for the advanced laryngeal cancer patients was the complete neck management after the operation and prophylactic neck dissection.