Korean J Med.  2014 Mar;86(3):271-276. 10.3904/kjm.2014.86.3.271.

Severe Fever with Thrombocytopenia Syndrome

• Kim KH
• Oh MD

• KMID: 1867354
• DOI: http://doi.org/10.3904/kjm.2014.86.3.271

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is firstly reported in China in 2011. It is an emerging infectious disease in China, Japan and South Korea. It is caused by novel bunyavirus, called SFTS virus. The vector of SFTS is Haemaphysalis longicornis tick and domesticated animals may serve as intermediate hosts. The clinical manifestations of SFTS are fever, vomiting, diarrhea, thrombocytopenia and leukopenia. In severe cases, multiple organ failure, disseminated intravascular coagulopathy, and central nervous systems manifestation are present. The case-fatality rate is 6-30%. There is no effective antiviral therapy and supportive care is the main treatment.

Keyword

Severe fever with thrombocytopenia syndrome; Phlebovirus; Bunyavirus

MeSH Terms

Animals, Domestic
Central Nervous System
China
Communicable Diseases, Emerging
Diarrhea
Fever*
Japan
Leukopenia
Multiple Organ Failure
Orthobunyavirus
Phlebovirus
Republic of Korea
Thrombocytopenia*
Ticks
Viruses
Vomiting