Korean J Med.
2014 Jan;86(1):89-95. 10.3904/kjm.2014.86.1.89.
A Case of Cerebellopontine Angle Diffuse Large B Cell Lymphoma in a Systemic Lupus Erythematosus Patient
- Affiliations
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- 1Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea. Junglim3@gmail.com
- 2Department of Pathology, Daegu Fatima Hospital, Daegu, Korea.
- 3Department of Therapeutic Radiology, Daegu Fatima Hospital, Daegu, Korea.
- KMID: 1867324
- DOI: http://doi.org/10.3904/kjm.2014.86.1.89
Abstract
- Patients with systemic lupus erythematosus (SLE) are at higher risk for malignant lymphomas, among which, however, primary CNS lymphoma (PCNSL) is rare. PCNSL usually occurs within the cerebral hemispheres, occasionally in the cerebellum, but rarely in the cerebellopontine angle (CPA). We report our findings in a 45-year-old man with SLE on azathioprine, who presented with sudden hearing loss and dysphagia. The brain MRI revealed a mass lesion in the right CPA. A biopsy was performed and the final diagnosis was diffuse large B cell lymphoma. This is the first report of CPA lymphoma in a SLE patient. The patient was treated with whole brain radiotherapy only because of recurrent pneumonia that was a result of dysphagia from permanent cranial nerve injury. He has been in complete remission for over 10 months.
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