Korean J Gastroenterol.  2001 Jul;38(1):65-70.

Islet Autotransplantation Following Total Pancreatectomy in A Patient with Recurrent Gastrointestinal Bleeding due to Arteriovenous Malformation of Pancreas and Duodenum

• Han DJ
• Kim SC
• Kim TH
• We YM
• Cho KM
• Hong JJ

Abstract

Arterovenous malformation of the pancreas is extremely rare. It can be an obscure cause of gastrointestinal bleeding. Pancreas islet cell autotransplantation has been reported with the favorable success rate in patients who underwent extensive pancreatectomy. We describe a 60-year-old male patient with arteriovenous malformation of the pancreas who presented with recurrent gastrointestinal bleeding. Preoperative CT and angiogram revealed arteriovenous malformation in the whole pancreas. The patient was treated with total pancreatectomy and simultaneous islet cell autotransplantation. C-peptide in blood was recovered upto the preoperative level in seven days after transplantation. Blood glucose could be controlled with 8-12 units of intermediate acting insulin. Two years later, the patient had a weight gain of 3 kg and could keep blood glucose in normal range without fluctuation. Here, we report the first case of pancreas islet cell autotransplantation after total pancreatectomy in Korea.

Keyword

Ascaris lumbricoides; Bile duct stone; Liver abscess

MeSH Terms

Arteriovenous Malformations*
Ascaris lumbricoides
Autografts*
Blood Glucose
C-Peptide
Duodenum*
Hemorrhage*
Humans
Insulin
Islets of Langerhans
Korea
Liver Abscess
Male
Middle Aged
Pancreas*
Pancreatectomy*
Reference Values
Weight Gain
Blood Glucose
C-Peptide
Insulin