Korean Circ J.  2007 Feb;37(2):64-71. 10.4070/kcj.2007.37.2.64.

Sex Differences of the Clinical Characteristics and Early Management in the Korea Acute Myocardial Infarction Registry

• Lee KH
• Jeong MH
• Ahn YK
• Kim JH
• Chae SC
• Kim YJ
• Hur SH
• Seong IW
• Hong TJ
• Choi DH
• Cho MC
• Kim CJ
• Seung KB
• Chung WS
• Jang YS
• Cho JG
• Park SJ

• KMID: 1859083
• DOI: http://doi.org/10.4070/kcj.2007.37.2.64

Abstract

BACKGROUND AND OBJECTIVES: The first on-line registration of Korea Acute Myocardial Infarction patients (KAMIRs) has been carried out throughout the 41 primary percutaneous coronary intervention (PCI) centers that are supported by the Korean Circulation Society (KCS), as reported in the memorandum of the 50th Anniversary of the KCS.
SUBJECTS AND METHODS
Between Nov 2005 and June 2006, 4905 patients were enrolled in KAMIR and 4110 eligible patients (2855 males and 1255 females; mean age=64.3+/-13.5 years) were analyzed. The treatment strategy for acute myocardial infarction (AMI) was analyzed according to the gender differences in the area of acute ST segment elevation myocardial infarction (STEMI) and non-ST segment elevation myocardial infarction (NSTEMI).
RESULTS
For the initial selection of a treatment strategy for STEMI, primary PCI was more commonly performed in males than females (69.8% vs. 68.3%, respectively, p=0.008), but age was the most important predictors after multivariate adjustment. During the hospital stay, PCI regardless of its subtype was more commonly done in the males than in the females with both STEMI and NSTEMI (STEMI: 89.1% vs. 84.9%, respectively, p=0.004; NSTEMI: 74.7% vs. 63.5%, respectively, p<0.001). The success rate of PCI in STEMI patients was not different between the genders (95.0% vs. 93.6%, respectively, p=0.399), but that of NSTEMI was higher in the males than the females (96.9% vs. 95.8%, respectively, p=0.004).
CONCLUSION
For the initial treatment of AMI in Korea, females are treated more conservatively than males, but age was the most important predictor for invasive treatment. The success rate of PCI was higher for the males than the females.

Keyword

Sex; Myocardial infarction; Angioplasty; Thrombolytic therapy; Stents

MeSH Terms

Angioplasty
Anniversaries and Special Events
Female
Humans
Korea*
Length of Stay
Male
Myocardial Infarction*
Percutaneous Coronary Intervention
Sex Characteristics*
Stents
Thrombolytic Therapy

Figure

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  Fig. 1 Initial therapeutic strategy in acute ST-segment elevation myocardial infarction. PCI: percutaneous coronary intervention.

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  Fig. 2 The rate of percutaneous coronary intervention during hospitalization. STEMI: acute ST segment elevation myocardial infarction, NSTEMI: acute non-ST segment elevation myocardial infarction.

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  Fig. 3 Stent types in percutaneous coronary intervention. STEMI: acute ST segment elevation myocardial infarction, NSTEMI: acute non-ST segment elevation myocardial infarction, Taxus: taxus stent, BMS: bare metal stent, Cypher: cypher stent.

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