Korean Circ J.  1998 Mar;28(3):339-349. 10.4070/kcj.1998.28.3.339.

Comparison of Dietary Intakes, Smoking Status, Plasma Lipids, Lipoprotein (a) and Antioxidant Nutrients in Patients With Coronary Heart Disease and Healthy Controls

• Jeon SM
• Park WH
• Jun JE
• Lee YK
• Park YB
• Choi MS

• KMID: 1858131
• DOI: http://doi.org/10.4070/kcj.1998.28.3.339

Abstract

BACKGROUND
Hyperlipidemia has been known as an independent risk factor in the develop-ment of coronary artery disease. This study was carried out to compare nutrient intakes, smo-king status, antioxidant vitamins, and plasma lipids in patients with coronary heart disease (CHD) and in normal healthy subjects among Korean population in Taegu. Possible causes of this dis-ease in patients are discussed.
METHODS
Anthropometric assessments included mean intakes of nutrients, and the levels of plasma lipids (apolipoprotein [Apo] A - I, Lipoprotein [Lp] [a]), and antioxidant vitamins (such as vitamins A and E) were measured in female and male subjects with CHD against healthy con-trols.
RESULTS
Dietary cholesterol and fat intakes were significantly higher in CHD groups in men and women. Total plasma cholesterol, LDL-C, triglyceride, thiobarbituric acid reactive subst-ance (TBARS), atherogenic index and Lp (a) levels were significantly higher in CHD patients than in the normal group in both men and women. Apo A-I, HDL-C and vitamin E levels were lower in CHD patients than in the normal group. The number of smokers was higher in CHD patients than in the normal group in both sexes of subjects.
CONCLUSION
High fat and high cholesterol intakes seemed to be a major factor for the hyperlipidemia in the CHD patients. Their abnormal lipoprotein profile, which appeared in pati-ent plasma, corresponded well to dietary intake patterns. However, long term studies are need-ed to investigate the effects of smoking on lipid metabolism in CHD patients among the Korean population.

Keyword

Smoking; Lipid metabolism; Coronary heart disease; Apolipoprotein A-I; Lipoprotein (a); Lipid peroxidation; Vitamin A; Vitamin E

MeSH Terms

Apolipoprotein A-I
Cholesterol
Cholesterol, Dietary
Coronary Artery Disease
Coronary Disease*
Daegu
Female
Humans
Hyperlipidemias
Lipid Metabolism
Lipid Peroxidation
Lipoprotein(a)*
Lipoproteins*
Male
Plasma*
Risk Factors
Smoke*
Smoking*
Triglycerides
Vitamin A
Vitamin E
Vitamins
Apolipoprotein A-I
Cholesterol
Cholesterol, Dietary
Lipoprotein(a)
Lipoproteins
Smoke
Vitamin A
Vitamin E
Vitamins