Korean J Pathol.  2005 Aug;39(4):269-272.

Giant Cell Tumor with an Unusual Cartilage Matrix: A Case Report

Affiliations
  • 1Department of Pathology, College of Medicine, Kyung Hee University, Seoul, Korea. ykpark@khmc.or.kr
  • 2Departments of Radiology, Kyung Hee University Hospital, Seoul 130-702, Korea. ykpark@khmc.or.kr
  • 3Departments of Orthopedic Surgery, Kyung Hee University Hospital, Seoul 130-702, Korea.

Abstract

Giant cell tumor of bone is a locally aggressive benign neoplasm, which is composed of oval or plump, spindle-shaped mononuclear cells and uniformly distributed multinucleated giant cells. Bone or cartilage matrix production by the tumor cells is usually not seen. We present a pathologically proven case of giant cell tumor, arising in the acetabulum and pubic bone, with unusual cartilage matrix production. We also discuss the differential diagnosis from a chondroblastoma as well as a giant cell-rich osteosarcoma.

Keyword

Giant cell tumor, Cartilage

MeSH Terms

Acetabulum
Cartilage*
Chondroblastoma
Diagnosis, Differential
Giant Cell Tumor of Bone
Giant Cell Tumors*
Giant Cells*
Osteosarcoma
Pubic Bone
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