The Role of Cervicography in the Screening of Cervical Cancer in Korean Women

Park, D C; Cho, S D; Lee, S H; Kim, T E; An, W S; Namkoong, S E; Kim, S J; Lee, H Y

Abstract

We did cervicographic and cytologic examiantion to confirm the possibility of national wide screening system. 1,308 women were prospectively screened in university hospital and private clinics between jan. 1995 and Sep. 1995. Cervigram were evaluated by at least 3 cervicography evaluators. 1,075 (82.1%) women had negative cervigram, 87 (6.6%) had atypical cervigram, 97 (9.8%) had positive cervigrams. 19 (1.5%) was technically defective. 5 invasive cancer were detected in this population. Cervical punch biopsy were token 84 womens because they had atypical or positive cervigram of abnormal cytology result in primal screening smears. Patients (82.1%) had negative cervigrams. 87 (6.6%) were technically defective. 5 invasive cancer were detected in this population. Among all positive cervigrams 1 of 8 invasive cancers had negative cytology and 27 of 48 cervical intraepithelial neoplasia lesion had negative cytology. The sensitivity of cervicography was 96.6%, the specificity of cervicography was 98.1%, positive predictive value of cervicography was 71.2%, negative predictive value was 99.3%, The false negative rate of cervicography was 3.4%, the false positive rate was 1.9%. The sensitivity of cytology was 52.5%, the specificity of cytology was 99.8%, positive predictive value of cytology was 91.2%, negative predictive value was 97.7%, The false negative rate of cytology was 47.5%, the false positive rate was 3%. Combined cytology and cervicography is more sensitive, specific and efficient for screening cervical cancer. We concluded cervicography had a potentiality as a adjunctive method for the national wide cervical cancer scrrening.