Obstet Gynecol Sci.  2014 Jul;57(4):330-333. 10.5468/ogs.2014.57.4.330.

Primary ovarian choriocarcinoma mimicking ectopic pregnancy

Affiliations
  • 1Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. bksong.kim@samsung.com

Abstract

Nongestational ovarian choriocarcinoma is an exceedingly rare and highly aggressive tumor. Although early diagnosis and timely initiation of therapy is important, it is difficult in reproductive aged patients because of the frequent elevation of human chorionic gonadotropin. We report a primarily nongestational ovarian choriocarcinoma in a 12-year-old virgin female. Initial diagnosis based on abdominopelvic computed tomography and pelvis magnetic resonance imaging was ectopic pregnancy with hemoperitoneum. A diagnostic laparoscopy of the ovarian tumor revealed choriocarcinoma. Unilateral salpingo-oophorectomy and omental sampling revealed surgical stage of IA. Six courses of adjuvant combination chemotherapy (bleomycin, etoposide, and cisplatin) followed surgery.

Keyword

Choriocarcinoma; Laparoscopy; Nongestational; Ovary

MeSH Terms

Child
Choriocarcinoma*
Chorionic Gonadotropin
Diagnosis
Drug Therapy, Combination
Early Diagnosis
Etoposide
Female
Hemoperitoneum
Humans
Laparoscopy
Magnetic Resonance Imaging
Ovary
Pelvis
Pregnancy
Pregnancy, Ectopic*
Chorionic Gonadotropin
Etoposide
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