J Korean Soc Transplant.  2013 Dec;27(4):185-189. 10.4285/jkstn.2013.27.4.185.

Toxoplasmosis after Kidney Transplantation

• Jeong YH
• Park JW
• Do JY
• Cho KH
• Kang SH
• Hwang MJ
• Choi EW
• Lee DW
• Yoon KW
• Kim YJ

• KMID: 1841127
• DOI: http://doi.org/10.4285/jkstn.2013.27.4.185

Abstract

Toxoplasmosis is an infection caused by Toxoplasma gondii. It can be lethal in immunocompromised hosts, such as a transplant recipients or patients infected with human immunodeficiency virus. In solid organ transplant recipients, toxoplasmosis results mainly from transmission of the parasite with an allograft in cases of serological mismatch. Toxoplasmosis in an immunocompromised host is associated with high mortality. Thus, early diagnosis and treatment is very important. We report on a case of toxoplasmosis in a 51-year-old male patient who had undergone deceased donor kidney transplantation. He suffered from fever of unknown origin. He was finally diagnosed with toxoplasmosis, and treated successfully with trimethoprim-sulphamethoxazole.

Keyword

Kidney transplantation; Toxoplasmosis; Fever

MeSH Terms

Early Diagnosis
Fever
Fever of Unknown Origin
HIV
Humans
Immunocompromised Host
Kidney Transplantation*
Kidney*
Male
Middle Aged
Mortality
Parasites
Tissue Donors
Toxoplasma
Toxoplasmosis*
Transplantation
Transplantation, Homologous
Transplants

Figure

• 

  Fig. 1. Proximal tubular epithelial cells show fine vacuolization in their cytoplasm. No inflammatory cell infiltration is noted along the interstitium. Arteriole shows focal hyalinosis of the donor change. Glomerulus has no specific changes (PAS, ×200).

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