J Korean Radiol Soc.  2005 Mar;52(3):191-197. 10.3348/jkrs.2005.52.3.191.

Usefulness of Apparent Diffusion Coefficient in Ovarian Cystic Tumors Using Diffusion-Weighted Magnetic Resonance Imaging

• Heo SH
• Jeong YY
• Song SG
• Kim JW
• Seo JJ
• Kim HJ
• Jeong GW
• Park JG
• Kang HK

• KMID: 1834230
• DOI: http://doi.org/10.3348/jkrs.2005.52.3.191

Abstract

PURPOSE
To evaluate the usefulness of apparent diffusion coefficient (ADC) values using diffusion-weighted magnetic resonance imaging (DWI) in patients with ovarian cystic tumors.
MATERIALS AND METHODS
During past 12 months, we studied 30 patients who were clinically suspected of having ovarian cystic tumors and who underwent DWI using a 1.5 T MR unit. Eight patients with small cystic ovarian lesions of less than 3 cm in diameter and insufficient DWI were excluded from the calculation of the ADC values. The remaining twenty-six cystic ovarian lesions in 22 patients were classified into four groups; ovarian cysts, cystadenomas, other benign tumors, and malignant tumors. DWI was obtained using single-shot spin echo planar imaging and two gradient steps (b values of 0, 800 sec/mm2). The ADC values were measured using regions-of-interest (ROI) in the cystic components of the DWI located in the same section as the T2-weighted image and away from the septation and solid components.
RESULTS
The mean ADC values were 0.196+/-0.105x10(-3) mm2/sec in the ovarian cysts, 1.312+/-1.064x10(-3) mm2/sec in the cystadenomas, 0.274+/-0.124x10(-3) mm2/sec in the other benign tumors, and 1.011+/-0.080x10(-3) mm2/sec in the malignant tumors. The differences in the ADC values between the ovarian cysts and cystadenomas, the ovarian cysts and malignant tumors, the cystadenomas and other benign tumors, and the other benign tumors and malignant tumors were statistically significant (p < 0.01). There was no statistically significant difference in the ADC values between the ovarian cysts and other benign tumors, or between the cystadenomas and malignant tumors (p > 0.05).
CONCLUSION
The calculated ADC values using DWI should be helpful in the differential diagnosis of cystic ovarian tumors.

Keyword

Ovary; Ovary, neoplasms; Ovary, MR

MeSH Terms

Cystadenoma
Diagnosis, Differential
Diffusion*
Echo-Planar Imaging
Female
Humans
Magnetic Resonance Imaging*
Ovarian Cysts*
Ovary