Korean J Hematol.  2012 Dec;47(4):307-308. 10.5045/kjh.2012.47.4.307.

Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia

• Kim MJ
• Yang JJ
• Meyer C
• Marschalek R
• Park TS

• KMID: 1832112
• DOI: http://doi.org/10.5045/kjh.2012.47.4.307

Abstract

No abstract available.

MeSH Terms

Leukemia, Promyelocytic, Acute
Translocation, Genetic

Figure

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  Fig. 1 Various RARA partner genes in acute promyelocytic leukemias.

Reference

1. Palta A, Dhiman P, Cruz SD. ZBTB16-RARα variant of acute promyelocytic leukemia with tuberculosis: a case report and review of literature. Korean J Hematol. 2012. 47:229–232.

2. Kang LC, Smith SV, Kaiser-Rogers K, Rao K, Dunphy CH. Two cases of acute myeloid leukemia with t(11;17) associated with varying morphology and immunophenotype: rearrangement of the MLL gene and a region proximal to the RARalpha gene. Cancer Genet Cytogenet. 2005. 159:168–173.

3. Yang JJ, Marschalek R, Meyer C, Park TS. Diagnostic usefulness of genomic breakpoint analysis of various gene rearrangements in acute leukemias: a perspective of long distance- or long distance inverse-PCR-based approaches. Ann Lab Med. 2012. 32:316–318.

4. Lim G, Cho EH, Cho SY, et al. A novel PML-ADAMTS17-RARA gene rearrangement in a patient with pregnancy-related acute promyelocytic leukemia. Leuk Res. 2011. 35:e106–e110.

5. Yang JJ, Park TS, Kim MJ, et al. Acute promyelocytic leukemia with trisomy 8 showing normal PML-RARA FISH signal patterns: diagnostic application of long-distance polymerase chain reaction in molecularly discrepant leukemia cases. Ann Hematol. 2012. 91:1645–1648.