J Korean Neurol Assoc.  1999 May;17(3):435-441.

2 cases of plasma cell granulomas involving intracranium

• Chun DW
• Ju SM
• Kim HW
• Kim BG
• Ahn BC
• Oh GS
• Yang KH

Abstract

Plasma cell Granuloma (PCG) is a form of idiopathic inflammatory pseudotumor (IPT). It is a rare entity character-ized by a nonneoplastic proliferation of inflammatory cells dominated by a polyclonal expansion of the plasma cells. This lesion has been discovered in many parts of the body including the central nervous system. We now report two cases of plasma cell granuloma involving the brain. The first case was a 42-year-old man who presented a right hemi-paresis. He had a lesion in the convexity of the left parietal region. The second case was a 58-year-old woman who was expressed confusion and a frontal-temporal headache. She had a lesion in the convexity of the left temporal region and mastoid bone. The diagnosis of PCG was confirmed by pathological and immunohistochemical studies revealing pre-dominant plasma cells in the affected tissues.

Keyword

Plasma cell granuloma; Inflammatory pseudotumor; Central nervous system

MeSH Terms

Adult
Brain
Central Nervous System
Diagnosis
Female
Granuloma, Plasma Cell*
Headache
Humans
Mastoid
Middle Aged
Plasma Cells*
Plasma*
Rabeprazole