Intest Res.
2012 Jul;10(3):272-279. 10.5217/ir.2012.10.3.272.
Comparison of Bowel Preparation Quality between Clear-liquid Diet and No Diet Restriction
- Affiliations
-
- 1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. diksmc.park@samsung.com
- 2Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
- 3Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
- 4Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
- 5Department of Internal Medicine, Hanyang University College of Medicine, Guri, Korea.
- KMID: 1807260
- DOI: http://doi.org/10.5217/ir.2012.10.3.272
Abstract
- BACKGROUND/AIMS
Adequate bowel preparation is essential for full visualization of colonic mucosa because detection of small polyps and neoplasms depends on the quality of bowel cleansing. The aims of this study were to compare the efficacy, tolerability of preparation and side effect between two groups: clear-liquid diet with polyethylene glycol (PEG) solution versus no diet restriction with PEG solution.
METHODS
This was a randomized single-blind prospective study. A total of 330 patients were randomly assigned to receive either 2 L PEG solution with a clear-liquid diet on the day before colonoscopy and another 2 L PEG solution on the day of the procedure (group 1) or 2 L PEG solution with a general diet on the day before colonoscopy and another 2 L PEG solution on the day of the procedure (group 2).
RESULTS
162 patients were assigned to group 1 and 168 patients to group 2. The satisfactory quality of bowel preparation was not significantly different between the two groups (80.2%, 78.6%, P=0.707). Patient's compliance of the clear-liquid diet in group 1 was 50%. The satisfactory quality of bowel preparation was weakly better when the clear-liquid diet was given 2 or 3 times a day (group 1A) than 0 or once a day (group 1B) (74.1%, 86.4%, P=0.048). The tolerability of the PEG solution and side effects of preparation were not significantly different in the two groups (P=0.573, 0.686).
CONCLUSIONS
Bowel preparation with no diet restriction and split-dose PEG solution was similar to preparation with a clear-liquid diet in efficacy, tolerability and side effect. Therefore, the use of the clear-liquid diet protocol should improve patient's compliance.
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