J Korean Med Sci.  2012 Mar;27(3):255-260. 10.3346/jkms.2012.27.3.255.

Health-Related Quality of Life Using the EuroQol 5D Questionnaire in Korean Patients with Type 2 Diabetes

Affiliations
  • 1Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea.
  • 2Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
  • 3Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
  • 4Department of Regulatory Affairs & Market Access, Sanofi-Aventis Korea Co. Ltd., Seoul, Korea.
  • 5Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul, Korea. mdjominwoo@paran.com

Abstract

We aimed; 1) to determine the validity of the EuroQol 5D (EQ-5D) for the health-related quality of life (HRQOL) of Korean patients with type 2 diabetes, and 2) to identify associated factors of the HRQOL of these patients. Follow-up surveys were conducted for consecutive patients with type 2 diabetes. HRQOL was assessed using the EQ-5D and the Short Form-36 (SF-36). The validity of EQ-5D was assessed with the perspectives of known group, convergent and discriminant validity. Additionally, a linear mixed model using a backward elimination was used for identify associated factors. Of the 1,072 patients included in the first survey, 858 (80.0%) completed the questionnaires in the follow-up. In the known group validity, the problem rates in each EQ-5D dimension were highest among women, elderly people, and less-educated subjects. The Spearman's rho between the EQ-5D and the SF-36 scales were larger in the comparable dimensions than those in the less comparable dimensions. In the final model, we found that sex, age, education, body mass index, atrial fibrillation, stroke, and retinopathy were statistically significant. Our data suggest that the EQ-5D is a valid tool for Korean patients with type 2 diabetes and that various factors could affect their HRQOL.

Keyword

EQ-5D; Health-Related Quality of Life; Diabetes Mellitus, Type 2

MeSH Terms

Adult
Aged
Aged, 80 and over
Diabetes Mellitus, Type 2/complications/*physiopathology/psychology
Female
Humans
Male
Middle Aged
*Quality of Life
Quality-Adjusted Life Years
*Questionnaires
Republic of Korea
Young Adult

Figure

  • Fig. 1 Differences in eight SF-36 scales with regards to reports of "no problems" and "some or severe problems" in each EQ-5D domain. *P < 0.05. PF, physical functioning; RP, role-physical; BP, bodily pain; GH, general health; VT, vitality; SF, social functioning; RE, role-emotional; MH, mental health.


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