J Korean Med Sci.  2010 Dec;25(12):1710-1715. 10.3346/jkms.2010.25.12.1710.

Segmentation of Cerebral Gyri in the Sectioned Images by Referring to Volume Model

• Park JS
• Chung MS
• Chi JG
• Park HS
• Shin DS

• KMID: 1792892
• DOI: http://doi.org/10.3346/jkms.2010.25.12.1710

Abstract

Authors had prepared the high-quality sectioned images of a cadaver head. For the delineation of each cerebral gyrus, three-dimensional model of the same brain was required. The purpose of this study was to develop the segmentation protocol of cerebral gyri by referring to the three-dimensional model on the personal computer. From the 114 sectioned images (intervals, 1 mm), a cerebral hemisphere was outlined. On MRIcro software, sectioned images including only the cerebral hemisphere were volume reconstructed. The volume model was rotated to capture the lateral, medial, superior, and inferior views of the cerebral hemisphere. On these four views, areas of 33 cerebral gyri were painted with colors. Derived from the painted views, the cerebral gyri in sectioned images were identified and outlined on the Photoshop to prepare segmented images. The segmented images were used for production of volume and surface models of the selected gyri. The segmentation method developed in this research is expected to be applied to other types of images, such as MRIs. Our results of the sectioned and segmented images of the cadaver brain, acquired in the present study, are hopefully utilized for medical learning tools of neuroanatomy.

Keyword

Visible Human Projects; Frozen Sections; Anatomy, Cross-Sectional; Cerebrum; Neuroanatomy; Brain Mapping; Imaging, Three-Dimensional

MeSH Terms

Aged
Cerebrum/*anatomy & histology
Humans
Imaging, Three-Dimensional
Male
*Models, Anatomic
Software

Figure

• 

  Fig. 1 Sectioned and segmented images generated in sequence. In the original sectioned images of head (A row), only cerebrum is segmented (B row) to acquire the sectioned images of the cerebrum (C row). Each gyrus of the cerebrum is then segmented (D row).

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  Fig. 2 Gyri segmentation referring to the volume model of the cerebrum. Lateral (A), medial (B), superior (C), and inferior (D) views of the volume model of the left cerebral hemisphere, on which entire cerebral gyri are painted with different colors; printed paper of a sectioned image, on which the cerebral gyri are delineated and annotated by pen (E) to elaborate segmented image of the gyri (F).

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  Fig. 3 Coronal, sagittal planes of the sectioned images and segmented images. Coronal sectioned image (A), coronal segmented image (B), sagittal sectioned image (C), and sagittal segmented image (D) are produced for verification of segmentation.

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  Fig. 4 Volume/surface models of the cingulate and parahippocampal gyri. Volume model of the gyri built on MRIcro (A column) and colored surface model of the gyri and cerebral hemisphere reconstructed on Maya (B column) are slightly rotated.

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  Fig. 5 Two-dimensional images, superimposed on the three-dimensional image of head. The corresponding segmented image (A), MRI (B), sectioned image (C), which are oriented on the surface model of the same cadaver, are compared with one another.

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