Korean J Intern Med.  2014 May;29(3):375-378. 10.3904/kjim.2014.29.3.375.

A case of ampullary gangliocytic paraganglioma

Affiliations
  • 1Division of Gastroenterology, Department of Internal Medicine, Inje University Busan Paik Hospital, Busan, Korea. cwj1225@naver.com
  • 2Department of Pathology, Inje University Busan Paik Hospital, Busan, Korea.

Abstract

Gangliocytic paragangliomas (GPs) are rare tumors of the duodenum, presenting as single sessile or pedunculated polypoid masses. Clinical manifestations of duodenal GPs can vary from an incidental finding at endoscopy to frequent upper gastrointestinal bleeding caused by mucosal ulceration and abdominal pain. GPs are considered benign, but the disease can recur and spread to regional lymph nodes. A 41-year-old female presented with abdominal pain. Upper gastrointestinal endoscopy revealed a subepithelial tumor of the ampulla of Vater in the second portion of the duodenum. The tumor was resected using the endoscopic mucosal resection technique. The tumor was diagnosed as benign GP of the duodenum using histological and immunohistochemical staining procedures.

Keyword

Paragangliomas; Duodenum

MeSH Terms

Adult
Ampulla of Vater/chemistry/*pathology/surgery
Biopsy
Duodenal Neoplasms/chemistry/*pathology/surgery
Duodenoscopy
Female
Humans
Immunohistochemistry
Paraganglioma/chemistry/*pathology/surgery
Treatment Outcome
Tumor Markers, Biological/analysis
Tumor Markers, Biological
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