Korean J Intern Med.
2014 Jan;29(1):96-100. 10.3904/kjim.2014.29.1.96.
Duodenal adenocarcinoma following a neuroendocrine tumor in the duodenum
- Affiliations
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- 1Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. swoopark@yuhs.ac
- 2Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
- 3Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
- KMID: 1792017
- DOI: http://doi.org/10.3904/kjim.2014.29.1.96
Abstract
- Primary duodenal adenocarcinoma is a rare malignant neoplasm accounting for 0.3% of all gastrointestinal tract carcinomas. We herein present one case of duodenal adenocarcinoma after duodenal neuroendocrine carcinoma. Poorly differentiated duodenal neuroendocrine carcinoma with liver metastasis (TxNxM1) was confirmed, and eight cycles of palliative chemotherapy (5-fluorouracil/etoposide/cisplatin) were administered. The patient was then in a clinically complete response status. About 1 year later, newly developed adenocarcinoma was detected at the same site. It was completely surgically resected, and the patient was cured.
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