Korean J Dermatol.
1999 Jul;37(7):912-916.
A Case of Multicentric Reticulohistiocytosis
- Affiliations
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- 1Department of Dermatology, Inje University, College of Medicine, Seoul, Korea.
- 2Department of Internal Medicine, Inje University, College of Medicine, Seoul, Korea.
- 3Department of Pathology, Inje University, College of Medicine, Seoul, Korea.
- 4Department of Dermatolgy, Samsung Hospital, Masan, Korea.
Abstract
- Multicentric reticulohistiocytosis(MR) is a rare systemic disease of unknown etiology, characterized by destructive polyarthritis and mucocutaneous eruptions in various locations. In most cases rapidly progressive destructive polyarthritis is the presenting symptom, followed by typical skin eruptions. Skin lesions are characterized clinically by erythematous to brownish nodular lesions on the face, periungual areas and the trunk. The biopsy demonstrating the characteristic granulomatous infiltration of multinucleated giant cells and histiocytes with a ground-glass appearance is diagnostic. We report a case of multicentric reticulohistiocytosis in a 57-year-old female patient, who had skin lesions with polyarthritis and cardiac problem. To our knowledge, this is the first case report in Korea.
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