J Korean Med Sci.  2013 Apr;28(4):580-585. 10.3346/jkms.2013.28.4.580.

Association between Maternal Characteristics and Neonatal Birth Weight in a Korean Population Living in the Seoul Metropolitan Area, Korea: A Birth Cohort Study (COCOA)

Affiliations
  • 1Department of Pediatrics, CHA Medical Center, CHA University School of Medicine, Seoul, Korea.
  • 2Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 3Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
  • 4Department of Pediatrics, Childhood Asthma Atopy Center, Research Center for Standardization of Allergic Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sjhong@amc.seoul.kr
  • 5Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 6Department of Pediatrics, Korean Cancer Hospital, Seoul, Korea.
  • 7Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 8Department of Pediatrics, Inje University Haeundae Paik Hospital, Busan, Korea.
  • 9Department of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, Korea.
  • 10Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 11Department of Pediatrics, Inje University Seoul Paik Hospital, Seoul, Korea.
  • 12Department of Pediatrics, Korea University College of Medicine, Seoul, Korea.
  • 13Department of Pediatrics, Hallym Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
  • 14Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.
  • 15Department of Pediatrics, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
  • 16Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea.
  • 17Department of Obstetrics and Gynecology, CHA University School of Medicine, Seoul, Korea.
  • 18Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Previous studies suggest that maternal characteristics may be associated with neonatal outcomes. However, the influence of maternal characteristics on birth weight (BW) has not been adequately determined in Korean populations. We investigated associations between maternal characteristics and BW in a sample of 813 Korean women living in the Seoul metropolitan area, Korea recruited using data from the prospective hospital-based COhort for Childhood Origin of Asthma and allergic diseases (COCOA) between 2007 and 2011. The mean maternal age at delivery was 32.3 +/- 3.5 yr and prepregnancy maternal body mass index (BMI) was 20.7 +/- 2.5 kg/m2. The mean BW of infant was 3,196 +/- 406 g. The overall prevalence of a maternal history of allergic disease was 32.9% and the overall prevalence of allergic symptoms was 65.1%. In multivariate regression models, prepregnancy maternal BMI and gestational age at delivery were positively and a maternal history of allergic disease and nulliparity were negatively associated with BW (all P < 0.05). Presence of allergic symptoms in the mother was not associated with BW. In conclusion, prepregnancy maternal BMI, gestational age at delivery, a maternal history of allergic disease, and nulliparity may be associated with BW, respectively.

Keyword

Cohort Studies; Birth Weight; Infant, Newborn; Mothers; Family Characteristic; Body Mass Index; Allergy and Immunology

MeSH Terms

Adult
*Birth Weight
Body Mass Index
Cohort Studies
Female
Gestational Age
Humans
Hypersensitivity/diagnosis/epidemiology
Infant, Newborn
Linear Models
Male
*Mothers
Parity
Pregnancy
Republic of Korea/epidemiology

Figure

  • Fig. 1 Flow chart of study population.


Cited by  1 articles

Trends in Birth Weight and the Incidence of Low Birth Weight and Advanced Maternal Age in Korea between 1993 and 2016
Hye-Eun Kim, In Gyu Song, Sung-Hoon Chung, Yong-Sung Choi, Chong-Woo Bae
J Korean Med Sci. 2019;34(4):.    doi: 10.3346/jkms.2019.34.e34.


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