J Periodontal Implant Sci.  2010 Oct;40(5):227-231. 10.5051/jpis.2010.40.5.227.

Socket preservation using deproteinized horse-derived bone mineral

• Park JY
• Koo KT
• Kim TI
• Seol YJ
• Lee YM
• Ku Y
• Rhyu IC
• Chung CP

• KMID: 1783563
• DOI: http://doi.org/10.5051/jpis.2010.40.5.227

Abstract

PURPOSE
The healing process following tooth extraction apparently results in a pronounced resorption of the alveolar ridge. As a result, the width of alveolar ridge is reduced and severe alveolar bone resorption occurs. The purpose of this experiment is to clinically and histologically evaluate the results of using horse-derived bone mineral for socket preservation.
METHODS
The study comprised 4 patients who were scheduled for extraction as a consequence of severe chronic periodontitis or apical lesion. The extraction was followed by socket preservation using horse-derived bone minerals. Clinical parameters included buccal-palatal width, mid-buccal crest height, and mid-palatal crest height. A histologic examination was conducted.
RESULTS
The surgical sites healed uneventfully. The mean ridge width was 7.75 +/- 2.75 mm at baseline and 7.00 +/- 2.45 mm at 6 months. The ridge width exhibited no significant difference between baseline and 6 months. The mean buccal crest height at baseline was 7.5 +/- 5.20 mm, and at 6 months, 3.50 +/- 0.58 mm. The mean palatal crest height at baseline was 7.75 +/- 3.10 mm, and at 6 months, 5.00 +/- 0.82 mm. There were no significant differences between baseline and 6 months regarding buccal and palatal crest heights. The amount of newly formed bone was 9.88 +/- 2.90%, the amount of graft particles was 42.62 +/- 6.57%, and the amount of soft tissue was 47.50 +/- 9.28%.
CONCLUSIONS
Socket preservation using horse-derived bone mineral can effectively maintain ridge dimensions following tooth extraction and can promote new bone formation through osteoconductive activities.

Keyword

Bone resorption; Bone substitutes; Clinical trial; Tooth socket

MeSH Terms

Alveolar Process
Bone Resorption
Bone Substitutes
Chronic Periodontitis
Humans
Minerals
Osteogenesis
Tooth Extraction
Tooth Socket
Transplants
Bone Substitutes
Minerals

Figure

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  Figure 1 Clinical photograph of the socket preservation procedure. (A) Horse-derived bone minerals were placed into the extraction socket. (B) Primary closure was achieved. (C) Six months of healing. (D) Newly formed bone was incorporated with graft particles at reentry.

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  Figure 2 Radiographs of socket preservation and implant placement. (A) Before extraction of retained roots. (B) Six months of healing after placement of horse-derived bone mineral. (C) After implant fixture installation.

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  Figure 3 Histology from horse-derived bone mineral grafting sites after 6 months. New bones were formed in contact with graft particles (multiple stains; bar = 0.1 mm).

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