Yonsei Med J.  2011 Mar;52(2):347-350. 10.3349/ymj.2011.52.2.347.

Serum Anti-Saccharomyces Cerevisiae Antibodies in Greek Patients with Behcet's Disease

• Vaiopoulos G
• Lakatos PL
• Papp M
• Kaklamanis F
• Economou E
• Zevgolis V
• Sourdis J
• Konstantopoulos K

• KMID: 1779674
• DOI: http://doi.org/10.3349/ymj.2011.52.2.347

Abstract

We tested 59 Greek patients with Behcet's Disease (BD) for serum anti-Saccharomyces cerevisiae antibodies. No increase of these antibodies was detected in the cases compared to 55 healthy unrelated blood donors from the same population. This finding is in contrast with the correlation between Saccharomyces cerevisiae antibodies and BD as reported in other populations. It seems that environmental factors may contribute to disease expression in different populations, producing different effects according to the individual's genetic predisposition. Saccharomyces cerevisiae antibodies do not seem to be of any significance in the Greek population.

Keyword

Anti-Saccharomyces cerevisiae antibodies; Behcet's disease; Greece

MeSH Terms

Adolescent
Adult
Aged
Antibodies, Fungal/*immunology
Behcet Syndrome/*immunology/microbiology
Case-Control Studies
Female
Greece
Humans
Immunoglobulin A/immunology
Immunoglobulin G/immunology
Male
Middle Aged
Saccharomyces cerevisiae/*immunology
Young Adult

Figure

• 

  Fig. 1 Distribution of IgA and IgG serum ASCA levels in 58 Greek BD patients and 55 healthy blood donors from the same population. ASCA, anti-Saccharomyces cerevisiae antiodies.

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