Yonsei Med J.  2010 Nov;51(6):978-979. 10.3349/ymj.2010.51.6.978.

Claude's Syndrome Associated with Neurocysticercosis

• Song TJ
• Suh SH
• Cho H
• Lee KY

• KMID: 1779651
• DOI: http://doi.org/10.3349/ymj.2010.51.6.978

Abstract

Claude's syndrome is a distinctive brainstem syndrome characterized by ipsilateral third cranial nerve palsy with contralateral hemiataxia and is due to an intrinsic or extrinsic lesion in the midbrain. We report a case of Claude's syndrome caused by neurocysticercosis infection. A 68 year-old Asian man was admitted to our hospital because of ataxia, left ptosis, and diplopia. Brain magnetic resonance imaging (MRI) showed a cystic lesion in the midbrain, which was surrounded by ring enhancement and peripheral edema. Neurocysticercosis infection was diagnosed by the cerebral spinal fluid study. The patient was treated with albendazole and steroids. A follow-up brain MRI three months later demonstrated the disappearance of a surrounding brain edema and rim enhancement. The most common cause of Claude's syndrome is cerebrovascular disease and malignancy. However, there is no report caused by neurocysticercosis infection. Therefore, if we encounter Claude's syndrome, we should consider neurocysticercosis infection as one of the etiologic factors.

Keyword

Neurocysticercosis; Claude's syndrome; ataxia

MeSH Terms

Aged
Albendazole/therapeutic use
Brain/pathology
Brain Stem Infarctions/complications/*diagnosis/*epidemiology
Edema/pathology
Humans
Magnetic Resonance Imaging/methods
Male
Neurocysticercosis/complications/*diagnosis/*epidemiology
Steroids/therapeutic use