Korean J Gastroenterol.  2009 Aug;54(2):126-129. 10.4166/kjg.2009.54.2.126.

A Case of Primary Sigmoid Colon Mucosa-associated Lymphoid Tissue Lymphoma

• Jung CK
• Lee JH
• Lee CM
• Won JJ
• Baek YH
• Lee JM
• Lee SA

• KMID: 1775968
• DOI: http://doi.org/10.4166/kjg.2009.54.2.126

Abstract

The gastrointestinal (GI) tract is the most frequently involved site of mucosa-associated lymphoid tissue (MALT) lymphoma. Stomach is the most common site of involvement among the GI tract. However, MALT lymphoma of the large intestine is rare. A diagnosis is established by pathological examination of the surgical or endoscopic specimens. A 72-year-old man with low abdominal pain was diagnosed as a sigmoid MALT lymphoma, which was noted as an obstructing mass in a colonoscopic examination. A left hemicolectomy was performed, and the patient has had no recurrence postoperatively without any chemotherapy.

Keyword

Mucosa-associated lymphoid tissue lymphoma; Sigmoid

MeSH Terms

Aged
Colon, Sigmoid/*pathology
Colonoscopy
Diagnosis, Differential
Humans
Lymphoma, B-Cell, Marginal Zone/*diagnosis/pathology/radiography
Male

Figure

• 

  Fig. 1. Colonoscopic view of a large polypoid tumor causing nearly total obstruction in the sigmoid colon. The surface of this tumor was ulcerative and covered with exudates.

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  Fig. 2. Simple abdomen X-ray showed obstructive ileus.

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  Fig. 3. Microscopic findings. (A) Surgical specimens histologically showed diffuse proliferation of atypical small lymphocytes in the mucosa and submucosa layer (H&E stain, ×100). (B) In high power view, infiltrative lymphocytes were seen within the glandular epithelium (lymphoepithelial lesion) and the gland structures were destructed (H&E stain, ×200). (C) Immunohistochemical stain revealed infiltrative lymphocytes with immunoreactive for CD20 (CD20, ×200).

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