J Korean Med Sci.  2014 Apr;29(4):544-549. 10.3346/jkms.2014.29.4.544.

Trends in Hospitalized Acute Myocardial Infarction Patients with Heart Failure in Korea at 1998 and 2008

• Youn JC
• Seo SM
• Lee HS
• Oh J
• Kim MS
• Choi JO
• Lee HY
• Cho HJ
• Kang SM
• Kim JJ
• Baek SH
• Jeon ES
• Park HY
• Cho MC
• Oh BH

• KMID: 1774460
• DOI: http://doi.org/10.3346/jkms.2014.29.4.544

Abstract

Heart failure (HF) complicating acute myocardial infarction (AMI) is common and is associated with poor clinical outcome. Limited data exist regarding the incidence and in-hospital mortality of AMI with HF (AMI-HF). We retrospectively analyzed 1,427 consecutive patients with AMI in the five major university hospitals in Korea at two time points, 1998 (n = 608) and 2008 (n = 819). Two hundred twenty eight patients (37.5%) in 1998 and 324 patients (39.5%) in 2008 of AMI patients complicated with HF (P = 0.429). AMI-HF patients in 2008 were older, had more hypertension, previous AMI, and lower systolic blood pressure than those in 1998. Regarding treatments, AMI-HF patients in 2008 received more revascularization procedures, more evidence based medical treatment and adjuvant therapy, such as mechanical ventilators, intra-aortic balloon pulsation compared to those in 1998. However, overall in-hospital mortality rates (6.4% vs 11.1%, P = 0.071) of AMI-HF patients were unchanged and still high even after propensity score matching analysis, irrespective of types of AMI and revascularization methods. In conclusion, more evidence-based medical and advanced procedural managements were applied for patients with AMI-HF in 2008 than in 1998. However the incidence and in-hospital mortality of AMI-HF patients were not significantly changed between the two time points.

Keyword

Acute Myocardial Infarction; Heart Failure; Temporal Trend; Hospital Mortality

MeSH Terms

Acute Disease
Age Factors
Aged
Blood Pressure
Demography
Female
Heart Failure/complications/*diagnosis/mortality
Hospital Mortality/*trends
Humans
Hypertension/complications
Male
Middle Aged
Myocardial Infarction/complications/*diagnosis/mortality
Odds Ratio
Republic of Korea
Retrospective Studies

Figure

• 

  Fig. 1 Study flow chart. AMI, acute myocardial infarction; HF, heart failure; LVEF, left ventricular ejection fraction.

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