Korean J Parasitol.  1976 Dec;14(2):140-146. 10.3347/kjp.1976.14.2.140.

Expermental chemotherapeutic effects of niclofolan (Bayer 9015, Bilevon) on the animals infected with Paragonimus westermani or P. iloktsuenensis

Affiliations
  • 1Department of Parasitology and Institute for Tropical Endemic Diseases, College of Medicine, Korea University, Seoul, Korea.

Abstract

The new drug niclofolan (bayer 9015, Bilevon), 5,5'-dichloro-2,2'-dihydroxy-3, 3'-dinitrobiphenyl, has been used in the treatment of Paragonimus westermani in dogs and cats and P. iloktsuenensis in rats. It was proved that administration of daily dose of 1.0 mg/kg body weight for 3 days or in 2 doses of 2.0 mg/kg body weight by alternate days were evidently effective for the infected dogs, cats and rats with the lung flukes, and toxic manifestations were not found.


MeSH Terms

parasitology-helminth-trematoda
Paragonimus iloktsuenensis
paragonimiasis
Paragonimus westermani
dog
cat
rat
niclofolan-chemotherapy
niclofolan
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