Korean J Gastrointest Endosc.  2004 Dec;29(6):524-528.

A Case of Diffuse Infiltrative Colon Cancer Coexisting with Colonic Tuberculosis

• Ha CY
• Jung HK
• Ryu JH
• Jung HS
• Pyun GW
• Kim DY
• Moon IH
• Cho MS

Abstract

Inflammatory bowel disease has a potential risk of developing colorectal cancer. However, there is little causal relationship between intestinal tuberculosis and colon cancer because intestinal tuberculosis is curable disease and has relatively short disease course. But there were a few case reports of intestinal tuberculosis associated with colon cancer. Diffuse infiltrating colon cancer, characterized by tumor cells in the presence of inflammatory changes with much fibrosis, is very rare in the colon. We experienced a 49-year-old woman who had tuberculous colitis combined with diffuse infiltrative colon cancer. She visited our hospital because of chronic diarrhea and abdominal pain. Colonoscopy showed multiple geographic ulcers in the transverse colon and partial intestinal obstruction. Histological examination revealed non-caseating granuloma and Mycobacterium tuberculosis was cultured in biopsied tissue. She took an anti-tuberculosis drug for 2 weeks, but her symptoms were aggravated. Therefore, extended right hemicolectomy was performed and revealed mucin-secreting, diffuse infiltrating adenocarcinoma. Herein, we report a rare case of diffuse infiltrative colon cancer coexisting with colonic tuberculosis with a review of liferatures.

Keyword

Colon cancer; Colonic tuberculosis; Diffuse infiltrating cancer

MeSH Terms

Abdominal Pain
Adenocarcinoma
Colitis
Colon*
Colon, Transverse
Colonic Neoplasms*
Colonoscopy
Colorectal Neoplasms
Diarrhea
Female
Fibrosis
Granuloma
Humans
Inflammatory Bowel Diseases
Intestinal Obstruction
Middle Aged
Mycobacterium tuberculosis
Tuberculosis*
Ulcer