Korean J Gastroenterol.
2003 Apr;41(4):321-324.
A Case of Metastatic Hepatocellular Carcinoma Presenting with Isolated Gallbladder Polyp after Successful Treatment of the Primary Cancer
- Affiliations
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- 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. yyb10604@plaza.snu.ac.kr
- 2Department of Surgery, Pathology, Seoul National University College of Medicine, Seoul, Korea.
- 3Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
- 4Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Abstract
- Hepatocellular carcinoma (HCC) does not usually cause metastasis because of its lower metastatic potential as well as early detection of the tumor resulting from screening of the high-risk population. However, metastatic HCCs are observed occasionally in the lung, bone, biliary tree, and adrenal gland and rarely in the skin, orbit, and gallbladder. Several cases of metastatic HCC to the gallbladder without direct invasion have been reported in the literature. However, it is extremely rare that only metastatic HCC is detected with no evidence of recurrence of the primary cancer. We experienced a case of metastatic HCC located in the gallbladder of a 64-year-old man as a polypoid mass after twenty-two month disease-free interval. To our knowledge, this is the first report of an isolated metastatic HCC in the gallbladder without any evidence of recurrence of the HCC in the liver.
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