Yonsei Med J.  2009 Aug;50(4):594-598. 10.3349/ymj.2009.50.4.594.

A Case of Moyamoya Disease in a Girl with Thyrotoxicosis

• Lee R
• Sung K
• Park YM
• Yu JJ
• Koh YC
• Chung S

• KMID: 1758625
• DOI: http://doi.org/10.3349/ymj.2009.50.4.594

Abstract

Moyamoya disease is a cerebrovascular disorder of unknown cause, characterized by slowly progressive bilateral stenosis or occlusion of the internal carotid arteries and produces collateral vessels. Moyamoya syndrome has rarely been reported in association with Graves' disease, especially in children. Several reports suggest that a cerebral infarction might have occurred in patients with clinical and laboratory evidence of hyperthyroid function. We report a case of Moyamoya disease in a girl with Down syndrome and thyrotoxicosis, and we review the relevant literature. To our best knowledge, this is the first report of Moyamoya disease associated with thyrotoxicosis in a young person in Korea.

Keyword

Moyamoya disease; thyrotoxicosis; Down syndrome

MeSH Terms

Down Syndrome/complications
Female
Humans
Korea
Moyamoya Disease/*complications/*diagnosis
Thyrotoxicosis/*complications
Young Adult

Figure

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  Fig. 1 (A) Magnetic resonance imaging scans showing bilateral stenosis of MCA and ICA (↑). (B) It is prominent on the left side. Multiple chronic infarction on the left deep periventricular white matter (▵).

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  Fig. 2 Angiography showing bilateral occlusion of ICA around supraclinoid segment (↑) with some collateral vessels (Moyamoya vessels, ▵). ACA and MCA are not visible.

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