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J Korean Soc Radiol.  2013 Mar;68(3):197-200. 10.3348/jksr.2013.68.3.197.

Relapsing and Progressive Tumefactive Demyelinating Form of Central Nervous System Involvement in a Patient with Progressive Systemic Sclerosis

Affiliations
  • 1Department of Radiology, Catholic University of Daegu School of Medicine, Daegu, Korea.
  • 2Department of Radiology, Kyungpook National University Hospital, Daegu, Korea. leehuijoong@knu.ac.kr

Abstract

White matter hyper intensities (WMHI) on MRI are not rare in patients with progressive systemic sclerosis (PSS). In this presentation, WMHI were developed in both middle cerebellar peduncles and temporal white matter in a patient with PSS, and regressed after medication of high dose steroid. However, new lesions were developed in the subcortices of both precentral gyri, and progressed rapidly to tumefactive hyperintensity on MRI. We report an unusual relapsing and progressive tumefactive demyelinating form of central nervous system involvement in PSS.


MeSH Terms

Central Nervous System
Humans
Scleroderma, Diffuse
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