J Korean Radiol Soc.  2008 Oct;59(4):225-234. 10.3348/jkrs.2008.59.4.225.

The Diagnostic Accuracy of the 64-slice Multi-detector CT Coronary Angiography for the Assessment of Coronary Artery Stenosis in Symptomatic Patients

• Ko SM
• Yi JG
• Nam CW
• Kim DH

• KMID: 1748441
• DOI: http://doi.org/10.3348/jkrs.2008.59.4.225

Abstract

PURPOSE
We evaluated the diagnostic accuracy of a 64-slice multi-detector CT (MDCT) coronary angiography against a conventional coronary angiography (CCA) for the detection of significant stenosis (> or =50% lumen diameter narrowing).
MATERIALS AND METHODS
Sixty-four patients underwent a MDCT and a subsequent CCA to evaluate the presence of atypical chest pain or suspected coronary artery disease (CAD). A MDCT angiography was performed using a 64-slice MDCT-scanner (Sensation 64, slice collimation 32x0.6 mm). The coronary artery segments were classified according to a 15-segment model. The sensitivity, specificity, and diagnostic accuracy of the 64-slice MDCT for the detection or exclusion of significant CAD were calculated on a per-segment and per-patient basis.
RESULTS
Fifty-nine of the 64 (92%) coronary CT angiograms were of diagnostic image quality with 93.5% (809 of 865) of the coronary segments assessable by CT angiography. One-hundred two (12.6%) segments showed significant stenosis by CCA. Stenosis of 50% or greater was detected by sensitivity, specificity, accuracy, positive predictive valve, and negative predictive value on a per segment basis (89%, 99%, 97%, 90%, and 98%, respectively) and a per-patient basis (96%, 69%, 90%, 92%, and 82%, respectively).
CONCLUSION
The 64-slice MDCT coronary angiography demonstrated a high diagnostic accuracy for both the per-segment and per-patient analyses for this symptomatic patient group.

Keyword

Computed tomography (CT); Coronary angiography; Coronary vessels, CT; Coronary vessels, stenosis or obstruction

MeSH Terms

Angiography
Chest Pain
Constriction, Pathologic
Coronary Angiography
Coronary Artery Disease
Coronary Stenosis
Coronary Vessels
Humans
Sensitivity and Specificity