Korean J Ophthalmol.  1987 Dec;1(2):102-108. 10.3341/kjo.1987.1.2.102.

Treatment of blepharospasm with botulinum A toxin

Affiliations
  • 1Division of Ophthalmology, Eulji Hospital, Seoul, Korea.
  • 2Division of Ophfhalmoiogy, The Mt. Sinai Medical Center, Cleveland, Ohio, U.S.A.

Abstract

Thirty-nine patients with blepharospasm were treated with botulinum A toxin. Twenty-six patients had essential blepharospasm, and thirteen had a hemifacial spasm. A total of 113 injections were given, and the average follow-up was 14.6 months. The mean preinjection spasm intensity was 2.9+ and the mean postinjection spasm intensity was 0.7+. The mean interval between injections was 4.4 months. The treatment was effective, although transient, in all patients with essential blepharospasm and hemifacial spasm. The toxin had a prolonged effect on the patients who had previously undergone muscle stripping procedure. The side effects were mild, transient, and local.

Keyword

essential blepharospasm; hemifacial spasm; botulinum A toxin

MeSH Terms

Adult
Aged
Blepharospasm/*drug therapy
Botulinum Toxins/*therapeutic use
Eyelid Diseases/*drug therapy
Female
Humans
Male
Middle Aged
Time Factors
Botulinum Toxins
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