Korean J Radiol.  2008 Feb;9(1):84-86. 10.3348/kjr.2008.9.1.84.

Pancreatic Metastasis in a Child Suffering with Treated Stage 4 Neuroblastoma

Affiliations
  • 1Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. somatom25@hanmail.net
  • 2Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

We present here a very rare case of metastatic relapse in the pancreas of a 4-year-old boy who had been treated for stage 4 neuroblastoma. Computed tomography showed multiple metastatic masses in the pancreas with secondary pancreatitis. To the best of our knowledge, this is the first case report of pancreatic metastasis in a child with neuroblastoma.

Keyword

Neuroblastoma; Pancreas, metastasis; Metastasis

MeSH Terms

Adrenal Gland Neoplasms/diagnosis/*pathology
Child, Preschool
Contrast Media
Diagnosis, Differential
Diagnostic Imaging
Humans
Male
Neuroblastoma/diagnosis/*secondary
Pancreatic Neoplasms/diagnosis/*secondary

Figure

  • Fig. 1 A 4-year-old boy with pancreatic metastasis who had been treated for stage 4 neuroblastoma. A. Contrast-enhanced CT scan shows a 2.5 cm sized mass (arrow) in the left adrenal gland. Surgery was performed after chemotherapy. The pathologic diagnosis was ganglioneuroblastoma. B. Contrast-enhanced CT scan demonstrates multiple small low attenuated nodular lesions in the pancreas (arrows). C. CT at three weeks after B shows marked diffuse swelling of the pancreas with an increase in size of multiple pancreatic masses throughout the entire pancreas. There are multifocal peripancreatic fluid collections caused by the combined pancreatitis. D. Abdominal sonography performed two weeks after C shows dilated intrahepatic ducts (arrows) due to obstruction by the pancreatic mass.


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