J Korean Med Sci.  2004 Apr;19(2):305-308. 10.3346/jkms.2004.19.2.305.

Intravascular Papillary Endothelial Hyperplasia (Masson's Hemangioma) of the Liver: A New Hepatic Lesion

• Hong SG
• Cho HM
• Chin HM
• Park IY
• Yoo JY
• Hwang SS
• Kim JG
• Park WB
• Chun CS

• KMID: 1733496
• DOI: http://doi.org/10.3346/jkms.2004.19.2.305

Abstract

Intravascular papillary endothelial hyperplasia (Masson's hemangioma) is a disease characterized by exuberant endothelial proliferation within the lumen of medium-sized veins. In 1923, Masson regarded this disease as a neoplasm inducing endothelial proliferation, however, now it is considered to be a reactive vascular proliferation following traumatic vascular stasis. The lesion has a propensity to occur in the head, neck, fingers, and trunk. Occurrence within the abdominal cavity is known to be very rare, and especially in the liver, there has been no reported case up to date. The authors have experienced intravascular papillary endothelial hyperplasia of the liver in a 69-yr-old woman, and report the case with a review of the literature.

Keyword

Intravascular Papillary Endothelial Hyperplasia; Hemangioma; Liver

MeSH Terms

Aged
Angiography
Endothelium, Vascular/pathology
Female
Hemangioendothelioma/*pathology/surgery
Human
Liver/*blood supply/*pathology
Necrosis
Vascular Neoplasms/*pathology/surgery

Figure

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  Fig. 1 Abdominal CT shows a lobulated, heterogenous contrast enhancing, soft tissue mass involving the entire left hepatic lobe (10×7 cm). Note the focal nodular enhancement around the peripheral portion of the hepatic mass in arterial phase.

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  Fig. 2 Abdominal CT shows an increased extent of peripheral nodular contrast-enhancement with a persistent low density noncontrast-enhancing portion of the tumor centrally in delayed phase.

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  Fig. 3 Angiography shows some tumor-supplying arteries from the left hepatic artery. There is no evidence of gross invasion in the main arteries.

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  Fig. 4 MRCP shows no dilatation of intra- and extra-hepatic bile duct. The left intrahepatic duct is not visualized due to tumor replacement.

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  Fig. 5 The specimen shows an inhomogeneous, multinodular mass with a focal necrosis.

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  Fig. 6 H-E stained microscopic specimen (×40). The thrombotic material is fragmented and entrapped by the ingrowing endothelial cells. There is no soft tissue invasion, atypia, or significant necrosis.

Reference

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