J Korean Med Sci.  2000 Feb;15(1):103-104. 10.3346/jkms.2000.15.1.103.

Successful allogeneic bone marrow transplantation for childhood-onset refractory anemia with ringed sideroblasts

• Kook H
• Kim CJ
• Yoon WS
• Ryang DW
• Hwang TJ

• KMID: 1731244
• DOI: http://doi.org/10.3346/jkms.2000.15.1.103

Abstract

Refractory anemia with ringed sideroblasts (RARS) is an extremely rare type of myelodysplastic syndrome in children. We describe a 10-year-old boy with RARS presented with pancytopenia. He remained relatively stable with only a few transfusions until age of 20 years, when he underwent an allogeneic bone marrow transplantation (BMT) because of increased transfusion requirements. He remains in complete chimeric state at 20 months posttransplant with normal hematologic parameters. To our knowledge, this is the first description of successful BMT in a patient with childhood-onset RARS. The indication of BMT for this rare disorder in children is discussed.

Keyword

Anemia Sideroblastic; Myelodysplastic Syndromes; Child; Bone Marrow Transplantation; Transplantation, Homologous

MeSH Terms

Anemia, Refractory/therapy*
Anemia, Sideroblastic/therapy*
Bone Marrow Transplantation*
Case Report
Child
Human
Male
Transplantation, Homologous