Yonsei Med J.  1983 Dec;24(2):123-126. 10.3349/ymj.1983.24.2.123.

Scanning Electron Microscopic Study of the Eccrine Ostia of Mouse Foot Pads After Application of Antiperspirant

• Lee S
• Bang DS
• Cho CK

• KMID: 1729509
• DOI: http://doi.org/10.3349/ymj.1983.24.2.123

Abstract

Recently, a topical preparation of 5% propantheline bromide and 10% aluminum hydroxychloride in an emulsion ground substance was introduced as an effective antiperspirant. According to the literature, aluminum salts may produce functional closure of swet ducts. Nevertheless, histologic study has as yet failed to reveal a solid anatomic basis for occlusion. In this study, the scanning electron microscope (SEM) was used to demonstrate eccrine gland ostial occlusion due to topical 5% propantheline bromide and 10% aluminum hydroxychloride.

Keyword

SEM; Antiperspirant; Eccrine Ostia

MeSH Terms

Aluminum Hydroxide/pharmacology*
Animal
Eccrine Glands/drug effects*
Foot
Male
Mice
Mice, Inbred HRS
Microscopy, Electron, Scanning
Propantheline/pharmacology*
Sweat Glands/drug effects*