Tuberc Respir Dis.  2010 Mar;68(3):175-179. 10.4046/trd.2010.68.3.175.

A Case of Bronchilolitis Obliterans Organizing Pneumonia in a Patient with Ulcerative Colitis

• Lee HJ
• Park BH
• Son JY
• Jung JY
• Hwang S
• Chon YE
• Kim EY
• Lim JE
• Lee KJ
• Yoon YW
• Kim YS
• Kim SK
• Chang J
• Shim HS
• Cho SH
• Park MS

• KMID: 1728963
• DOI: http://doi.org/10.4046/trd.2010.68.3.175

Abstract

The ulcerative colitis is a chronic inflammatory bowel disease with an unknown etiology. The major symptoms of ulcerative colitis are diarrhea, abdominal pain and hematochezia. However, arthritis, skin disorders, hepatobiliary inflammation and uveitis are occasionally recognized as systemic complications. Although there are few reports of coexistent pulmonary and inflammatory bowel disease, the lung is not generally considered to be a target organ in ulcerative colitis. We report a patient with ulcerative colitis-related bronchilolitis obliterans organizing pneumonia confirmed by video-assisted thoracoscopic surgery, who responded to corticosteroid therapy.

Keyword

Colitis, Ulcerative; Lung; Cryptogenic Organizing Pneumonia

MeSH Terms

Abdominal Pain
Arthritis
Colitis, Ulcerative
Cryptogenic Organizing Pneumonia
Diarrhea
Gastrointestinal Hemorrhage
Humans
Inflammation
Inflammatory Bowel Diseases
Lung
Pneumonia
Skin
Thoracic Surgery, Video-Assisted
Ulcer
Uveitis

Figure

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  Figure 1 Initial Chest PA showed slightly increased reticular pattern in both lower lobes.

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  Figure 2 High resolution computed tomography (HRCT) at initial diagnosis showed irregular shaped nodules, air trapping, and bronchiectasia on both lower lobes (A, B). HRCT obtained after 3 months treatment on same level demonstrated improvement of previous noted lesions (C, D).

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  Figure 3 The histologic finding of the wedge resected lung tissue showed organizing fibrosis that predominantly involved bronchiolar lumens and peribronchiolar airspaces (A, H&E stain, ×100). The fibrosis was composed of elongated fibroblasts and chronic inflammatory cells embedded in a myxoid stroma (B, H&E stain, ×400).

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