Korean J Pathol.
1996 Jan;30(1):65-67.
Primary Malignant Melanoma arising in Mucosa of the Palatine Tonsil: A case report
- Affiliations
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- 1Department of Pathology, Wonkwang University Medical School, 570-749 Iksan, Korea.
- 2Department of Otolaryngology, Wonkwang University Medical School, 570-749 Iksan, Korea.
Abstract
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Maligant melanomas of the oral or nasal cavity, and the vulvovaginal area are relatively common among the melanomas of non-ocular mucosa. But, primary malignant melanoma arising in the mucosa of the palatine tonsil is rare. We present a case of primary malignant melanoma arising in the mucosa of the palatine tonsil. A 36-year-old male was admitted for evaluation of a recurrent sore throat. Tonsillectomy was performed on the basis of clinical suspicion of chronic tonsillitis. Grossly, the left tonsil was focally dark. Microscopically, the tonsillar mucosa was diffusely infiltrated with tumor cells. Tumor cells revealed numerous melanin pigments. Intraepithelial nests of tumor cells were noted, but pagetoid spread of tumor cells was not found. Tumor cells were positive for S-100 protein and HMB45 stain. There was no evidence of melanoma in the skin or eye.