Korean J Pathol.
1988 Jun;22(2):138-144.
Malignant Fibrous Histiocytoma of the Heart: A case report
- Affiliations
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- 1Department of Pathology, College of Medicine, Chung Nam National University, Taejeon, Korea.
- 2Department of Chest Surgery, College of Medicine, Chung Nam National University, Taejeon, Korea.
Abstract
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A case of a 58-year-old man with malignant fibrous histiocytoma (MFH) of the right ventricle is reported light and electron microscopically. This is the first case of MFH of the heart in the Korean literature. A tendency for malignant fibrous histiocytoma of the heart to occur in the left atrium of young women is suggested; this sarcoma's usual location is in the soft tissue of elderly men. The tumor consisted of spindle cells arranged in a focal storiform patterns, clusters or sheets of histocyte-like cells, benign and malignant giant cells, inflammatory cells, scattered mitotic figures and anaplasia of stromal cells. In ultrastructure the constituent of cells of the tumor are primitive mesenchymal cells, histiocytoid cells and fibroblast like cells including giant cells.