Korean J Med.
2013 Sep;85(3):329-333. 10.3904/kjm.2013.85.3.329.
A Case of Thymoma with Immunodeficiency (Good's Syndrome) with Disseminated Tuberculosis
- Affiliations
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- 1Division of Infectious Diseases, Chungnam National University Hospital, Daejon, Korea. medone@cnuh.co.kr
- 2Department of Medicine, Chungnam National University Hospital, Daejon, Korea.
- 3Department of Neurology, Chungnam National University Hospital, Daejon, Korea.
- KMID: 1722647
- DOI: http://doi.org/10.3904/kjm.2013.85.3.329
Abstract
- Good's syndrome is the rare association of immunodeficiency with thymoma, characterized by hypogammaglobulinemia, depleted B-cells, diminished T-cells and inversion of the CD4/CD8 ratio. Thymectomy does not usually improve hypogammaglobulinemia; thus, the patient remains prone to infections. Infections affect primarily the sinopulmonary and gastrointestinal system. Here we present a case of a 71-year-old woman with common manifestations of Good's syndrome who succumbed to disseminated tuberculosis. Serum immunoglobulin levels should be measured for patients with thymoma and susceptibility to infection.
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