Korean J Intern Med.  2007 Mar;22(1):55-58. 10.3904/kjim.2007.22.1.55.

Acral Metastasis in a Patient with Ampullary Carcinoma

Affiliations
  • 1Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea. medcsc@wmc.wonkwang.ac.kr
  • 2Department of Dermatology, Wonkwang University School of Medicine, Iksan, Korea.
  • 3Department of Pathology, Wonkwang University School of Medicine, Iksan, Korea.

Abstract

Although skin metastasis from a malignant tumor of an internal organ usually occurs at an advanced disease stage, there has been no prior report of a cutaneous acral metastasis from ampullary carcinoma to date. We report a 71-year old male patient with cutaneous metastasis from an ampullary adenocarcinoma. The patient had a history of pylorus preserving pancreaticoduodenectomy for carcinoma of the ampulla of Vater two years prior to presentation. Physical examination revealed ill-defined, painful and hard erythematous nodules at the left thumb and distal phalanx of the right middle finger. The computed tomography scan showed low density masses in the retroperitoneum; the histological examination of a nodule from the right middle finger showed a metastatic adenocarcinoma. This case illustrates that cutaneous metastasis from ampullary carcinoma has a poor prognosis.

Keyword

Ampulla of Vater; Adenocarinoma; Metastasis

MeSH Terms

Skin Neoplasms/*secondary
Prognosis
Male
Humans
Fatal Outcome
Common Bile Duct Neoplasms/*pathology
Ampulla of Vater/*pathology
Aged
Adenocarcinoma/*pathology
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