Korean J Intern Med.  2007 Mar;22(1):28-31. 10.3904/kjim.2007.22.1.28.

Hypertrophic Cardiomyopathy Complicated by Left Ventricular Apical Necrosis and Aneurysm in a Young Man: FDG-PET Findings

• Park JS
• Cho IH
• Shin DG
• Kim YJ
• Hong GR
• Shim BS

• KMID: 1717991
• DOI: http://doi.org/10.3904/kjim.2007.22.1.28

Abstract

A 29-year old male was transferred to our hospital with an abnormal chest X-ray finding diagnosed as hypertrophic cardiomyopathy with apical necrosis and aneurysm formation. Four years after the initial hospitalization, we confirmed the aneurysm and necrosis using both integrated positron emission tomography (PET) and computed tomography (CT) scanning. The F-18 2-fluoro-2-deoxy-D-glucose (FDG) PET/CT enabled precise localization of the aneurysm, which was found to be composed of semi-lunar calcification of non-metabolic myocardium. A contrast-enhanced CT angiography showed an hour-glass appearance of the left ventricular cavity. The integrated PET/CT fusion scanner is a novel multimodality technology that allows for a comprehensive analysis of the anatomical and functional status of complex heart disease. Based on these findings, long standing mechanical and physiologic abnormalities may have led to chronic ischemia in the hypertrophied myocardium, induced necrosis and calcification at the cardiac apex.

Keyword

Hypertrophic Cardiomyopathy; Aneurysm; Positron Emission Tomography

MeSH Terms

Tomography, X-Ray Computed
Positron-Emission Tomography
Necrosis/complications/*diagnosis
Male
Humans
Heart Ventricles/*pathology
Heart Aneurysm/complications/*diagnosis
Fluorodeoxyglucose F18/diagnostic use
Contrast Media
Cardiomyopathy, Hypertrophic/complications/*diagnosis
Angiography, Digital Subtraction
Adult