Korean J Radiol.  2013 Aug;14(4):640-642. 10.3348/kjr.2013.14.4.640.

Rapid Intra-Hepatic Dissemination of Hepatocellular Carcinoma with Pulmonary Metastases Following Combined Loco-Regional Therapy

• Pua U

• KMID: 1715769
• DOI: http://doi.org/10.3348/kjr.2013.14.4.640

Abstract

This manuscript describes an unusual case of rapid intra-hepatic dissemination of hepatocellular carcinoma with pulmonary metastases occurring 1 month after combined chemoembolization and radiofrequency ablation. Inferior vena cava and portal vein invasion tumor thrombus was also detected, possibly accounting for the mechanism of disease dissemination route of disease.

Keyword

Metastases; Hepatocellular carcinoma; Chemoembolization; Radiofrequency ablation

MeSH Terms

Aged, 80 and over
Antineoplastic Agents/administration & dosage/*adverse effects
Biopsy
Carcinoma, Hepatocellular/diagnosis/*secondary/therapy
Catheter Ablation/*adverse effects
Chemoembolization, Therapeutic/*adverse effects
Cone-Beam Computed Tomography
Fatal Outcome
Humans
Liver Neoplasms/*pathology/therapy
Lung Neoplasms/diagnosis/*secondary
Male
Antineoplastic Agents

Reference

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2. Ruzzenente A, Manzoni GD, Molfetta M, Pachera S, Genco B, Donataccio M, et al. Rapid progression of hepatocellular carcinoma after Radiofrequency Ablation. World J Gastroenterol. 2004; 10:1137–1140.

3. Mori Y, Tamai H, Shingaki N, Moribata K, Shiraki T, Deguchi H, et al. Diffuse intrahepatic recurrence after percutaneous radiofrequency ablation for solitary and small hepatocellular carcinoma. Hepatol Int. 2009; 3:509–515.

4. Kotoh K, Enjoji M, Arimura E, Morizono S, Kohjima M, Sakai H, et al. Scattered and rapid intrahepatic recurrences after radio frequency ablation for hepatocellular carcinoma. World J Gastroenterol. 2005; 11:6828–6832.