Korean J Gastroenterol.  2000 Apr;35(4):512-516.

Multiple Bone Metastases in a Patient with Small Hepatocellular Carcinoma

• Lee CH
• Kang JH
• Kim HY
• Han SM
• Kwack KK
• Park HK
• So SC
• Kim SE
• Park SJ
• Park YH

Abstract

Hepatocellular carcinoma (HCC) usually spreads to the lung and regional lymph nodes by direct extention, lymphatic route, and vascular dissemination. Rarely, it happens to metastasize to the bones. Metastases to other organs such as bones seem to occur by erosions of pulmonary veins into the systemic circulation or retrogradely, into vertebral venous plexuses via portal vein. Treatment results were poor with a median survival of 5 months. We experienced multiple bone metastases in a 61-year-old male patient with small HCC. In conclusion, this report is valuable in presenting unusual multiple bone metastases in small HCC.

Keyword

Hepatocellular carcinoma; Bone metastasis

MeSH Terms

Carcinoma, Hepatocellular*
Humans
Lung
Lymph Nodes
Male
Middle Aged
Neoplasm Metastasis*
Portal Vein
Pulmonary Veins